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Ketoacidosis occurs when the cells in the body cannot take up glucose efficiently. To stay alive, the cells look for energy from other sources such as fats and amino acids. When these break down, the products produce a large amount of acid that has to be eliminated from the body. When somebody comes into the emergency room in ketoacidosis, their blood pH may be anywhere from 6.8 to 7.2, which often overwhelms the buffer systems that are available.