Case Study: The Genetics of Resistance to HIV Infection
Deletion in Mutated sequence


Selected Answer: Deletes 10 amino acids without changing the reading frame.

Incorrect.

Three bases code for one amino acid, so a deletion of 10 amino acids would correspond to a deletion of 30 nucleo-tides. Because 32 nucleotides are deleted in the Δ32 allele, this removes the information for 10 2/3 amino acids, and shifts the reading frame of the gene.

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