Case Study: The Genetics of Resistance to HIV Infection

CCR5 Genotype Test
Here are the results of testing the CCR5 gene in three individuals: an EU man, one of his parents, and a control individual (not necessarily in that order).

Use the results to determine each person’s genotype. Then determine which one is EU.

INSTRUCTIONS:
First, determine the correct genotype for the individuals.

Then select which individual is EU.

Graphic: Genotype Test Results


Which option describes the correct genotypes for the three indivduals?
    Individual 1 Individual 2 Individual 3
arrow Option A CCR5Δ32/CCR5Δ32 CCR5/CCR5 CCR5Δ32/CCR5Δ32

arrow Option B CCR5/CCR5 CCR5Δ32/CCR5Δ32 CCR5/CCR5Δ32

arrow Option C CCR5/CCR5 CCR5/CCR5 CCR5/CCR5Δ32