Teacher resources and professional development across the curriculum

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Sub Image2:Macro to Micro Structures
         
 
Workshops
1) Atoms and Molecules2) Macro to Micro Structures 3) Energetics and Dynamics 4) Theory and Practice in Chemical Systems 5) Chemical Design
6) The Chemistry of Life7) Chemistry and the Environment8) Chemistry at the Interface
 

Unit 5.6 Mixture Design and Separation
By separating the components of colored markers using chromatography, students gain insight into how the markers are designed and made. Chromatographic methods are used in industry and in research for a wide range of analyses and design.
Video program cues: 44:05-57:25

Separating mixtures laboratory

Veatta Berry teaches her students about solvent separation through paper chromatography of markers.

Activity

Links

Reading
JCE Editorial Staff (2000)' The Write Stuff: Using Paper Chromatography to Separate an Ink Mixture, 'Journal of Chemical Education, Vol. 77, No. 2, pp: 176A-176B.

Drug chromatography

"We are using chromatography not only for inks. In the same way inks separate, drugs separate as well. If you have heroin, cocaine, and codeine — those are all alcohol-type drugs. You can run them and they will separate. We use larger TLC plates for drugs because we want them to run a longer distance. In drugs it’s a single compound, and you will need a longer plate so it will separate in the correct shape. Now you can identify drugs with mass spectra, but we need to have a known to run with it, and the known we identify on a TLC plate. Just because a new technology comes out, doesn’t mean that this doesn’t work any more. We use it because it works."

Nellia Jenkins
Chemist, FBI Explosives Unit

Link

Reading
Long, G.A. (1995)' Simulation of a Forensic Chemistry Problem: A Multidisciplinary Project for Secondary School Chemistry Students, 'Journal of Chemical Education, Vol. 72, No. 9, pp: 803.

Combinatorial chemistry

"The beauty of chemistry has always been that there is an infinite number of ways that you can connect molecules. And we have not yet gotten close to getting all of the combinations. This is where the field of combinatorial chemistry comes about. That explores the many different ways to connect the different atoms to give you materials with different properties. It’s back to basic chemistry. Sticking together balls and sticks. If you can do that in your hand with balls and sticks, you can do that on the molecular level, because the rules of engagement are well known. How you put them together is only controlled by your own imagination."

Dr. Richard Wool
Professor of Chemical Engineering, University of Delaware

 

Link

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