Brainstem of transgenic mouse. To trace the longer pathways that interconnect different brain regions, CBS labs developed a genetic method to label each individual nerve cell a different color to identify and track axons and dendrites over long distances. With light microscopy, scientists image the branching patterns and connections of all the axons within a region of the nervous system in transgenic mice that express a number of different fluorescent proteins in individual neurons. The idea here is to color-code the individual “wires” and “nodes.”
Photographer: Jeff Lichtman
Source: Livet, Weissman, Sanes and Lichtman/Harvard University
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