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Unit 2: Proteins and Proteomics
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Books
Branden, C., and J. Tooze. 1998. Introduction to protein structure. New York: Garland Press.
A non-technical introduction to protein structure.

Ezzell, Carol. 2002. Scientific American: Beyond the human genome.
An e-book that describes the new biology after the human genome.


Articles
DeFrancesco, L. 2002. Probing protein interactions. The Scientist 16[8]:28.
Researchers have found them by the thousands, but what do these interactions mean?

Ezzell, C. 2002. Proteins rule. Scientific American 286:40–48.
Biotech’s latest mantra is “proteomics,” as it focuses on how dynamic networks of human proteins control cells and tissues.

Hollon, T. 2002. Software zeroes in on ovarian cancer. The Scientist 16[8]:16.
A proteomic fingerprint with unprecedented diagnostic accuracy becomes a new kind of disease biomarker.

Hopkin, K. 2001. The post-genome project. Scientific American 285:16.
Whether the human proteome will be successfully mapped in three years depends upon how you define “proteome.”

Lewis, R. 2002. Fighting the 10/90 gap. The Scientist 16[10]:22.
Initiative targets the most neglected diseases; how scientists can help.

McCook, A. 2002. Lifting the screen. Scientific American 286:16–17.
An accurate test is not always the best way to find cancer.

Sinclair, B. 2001. Software solutions to proteomics problems. The Scientist 15[20]:26.
Researchers find programs to aid every step of research.

Smutzer, G. 2001. Yeast: An attractive, yet simple model. The Scientist 15[18]:24.
Researchers use whole genome strategies to characterize unknown genes in yeast.

Stix, G. 1999. Parsing cells. Scientific American 287:36.
Proteomics is an attempt to devise industrial-scale techniques to map the identity and activities of all the proteins in a cell.
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