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Unit Chapters
Genomics
Proteins & Proteomics
What is Proteomics?
Introduction to Protein Structure
Determining Protein Structure
Structure and Function Relationships of Proteins
Protein Modification
Genomics-Based Predictions of Cellular Proteins
2D Gel Electrophoresis to Identify Cellular Proteins
Mass Spectrometry to Identify Cellular Proteins
Identifying Protein Interactions
The Yeast Two-Hybrid System
Protein Microarrays
Protein Networks
Proteomes in Different Organisms
Proteomics and Drug Discovery
Ethics and the Economics of Drug Discovery
Evolution & Phylogenetics
Microbial Diversity
Emerging Infectious Diseases
HIV & AIDS
Genetics of Development
Cell Biology & Cancer
Human Evolution
Neurobiology
Biology of Sex & Gender
Biodiversity
Genetically Modified Organisms
Protein Networks

The cell is a complex and dynamic system of networks of interacting molecules.
Figure 5: Protein interaction
An understanding of the cell requires analyzing these complex interactions as a system. Systems biology takes the approach that the powerful high-throughput techniques, developed as part of whole genome and proteome analysis, will allow the simultaneous study of complex interactions of networks of molecules, including DNA, RNA, and proteins. Fully understanding complex networks of molecular interactions in the cell requires a combination of several different experimental techniques, including DNA and protein microarrays, mass spectral analysis, and two-hybrid analysis. This, combined with the power of computers to analyze the massive amount of data, produces models of interacting networks, which better describe the workings of a cell (Fig. 5).
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