Case Study: Designing Cancer Drugs: Development of Gleevec

The development of a drug begins with basic research on a disease, which can take decades. (CML was first described in 1900.) Once the cause is defined, a pharmaceutical company must invest its research and development dollars into a treatment. While a drug is being planned and tested, companies say that it is “in the pipeline.” The general steps, which we’ll follow for Gleevec, are shown in the “Drug Development Pipeline” below. As we proceed, it will give us an idea of the time and cost for a drug to go “down the pipeline.”
Because the first step is to learn as much as possible about the disease, let’s start by learning about CML.

Click the CONTINUE button to begin the investigation.

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Drug Development Timeline