Protein Networks
The cell is a complex and dynamic system of networks of interacting molecules. An understanding of the cell requires analyzing these complex interactions as a system. Systems biology takes the approach that the powerful high-throughput techniques, developed as part of whole genome and proteome analysis, will allow the simultaneous study of complex interactions of networks of molecules, including DNA, RNA, and proteins. Fully understanding complex networks of molecular interactions in the cell requires a combination of several different experimental techniques, including DNA and protein microarrays, mass spectral analysis, and two-hybrid analysis. This, combined with the power of computers to analyze the massive amount of data, produces models of interacting networks, which better describe the workings of a cell (Fig. 5).
. |
